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Structural MRI analyses consistently show reduced gray matter volume in the prefrontal cortex (PFC), hippocampus, and anterior cingulate cortex (ACC) of chronic drinkers, regions integral to emotional regulation and stress response

Author contributions WQ designed the research and analyzed the data and wrote the manuscript

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Prescription retinoids like tretinoin are more potent than over-the-counter retinol

For example, increased NAD+/NADH ratios promote oxidative metabolism and gluconeogenesis, while decreased ratios favor reductive biosynthesis and lipid synthesis

Huang Y, et al